Fentanyl Protection: 5 Tips to Buying Fentanyl Gloves


As fentanyl overdose deaths continue to rise, nearly doubling from 2019-21, it is crucial for law enforcement officers, first responders and those in the healthcare fields to wear appropriate protective gear. As recommended by the White House, first responders should wear fentanyl protective gloves when the presence of fentanyl is suspected.

Fentanyl is a synthetic opioid up to 50 times more potent than heroin and 100 times stronger than morphine. Commonly used medically for pain management and anesthesia, fentanyl is also made and sold illegally as a recreational drug, often being mixed with heroin or cocaine - contributing to overdoses. Like other opioids, fentanyl use can lead to dependency and addiction, can be absorbed via the skin via open cuts and by inhalation. Even exposure to tiny amounts - as little as 2mg, about the size of 5 grains of salt - can cause respiratory depression, arrest and possible death. Fentanyl gloves of consistently high quality are an essential last line of defense for anyone who might come into accidental contact with the drug.

Do all gloves protect against fentanyl?

No. Nitrile gloves must be tested to the chemotherapy drug threshold (ASTM D6978) to claim resistance. To ensure the highest levels of safety, we recommend confirming the nitrile glove was specifically tested against a fentanyl solution. Not all gloves claiming fentanyl protection have been specifically tested against the substance.


The National Institute for Occupational Safety and Health (NIOSH) states, “No nitrile glove models showed fentanyl or carfentanil permeation rates above the chemotherapy drug threshold criterion of 0.01 µg/cm2/min (i.e., thereby meeting the performance requirement) as calculated using the ASTM D6978-19 standard within the 240-min test. Latex and vinyl glove materials exhibited fentanyl and carfentanil permeation with permeation rates above this threshold.”


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5 Tips to Buying Fentanyl Gloves

  1. Select the right glove type: 
    To prevent fentanyl exposure, NIOSH recommends emergency first responders ‘always wear nitrile gloves when illicit drugs may be present and change them properly when they become contaminated.’ Also recommending the use of powder-free nitrile gloves with a minimum thickness of 5+- 2mil. At Eagle, we strongly recommend using a nitrile glove with the ASTM D6978 rating that was specifically tested against a fentanyl solution, proving protection against this hazardous drug. For example, Eagle fentanyl gloves have been tested against a fentanyl citrate injection (100 mcg/2mL) solution and after 4 hours of exposure there was no breakthrough or permeation. As NIOSH has shown, latex and vinyl gloves are not recommended as they have not shown effective fentanyl protection. 
  2. Proper glove fit:
    The disposable nitrile glove should have a snug, but comfortable fit. A snug fit will ensure the glove stays in place during use, protecting the wearer from transdermal exposure.
  3. Durability:
    Only gloves manufactured with the highest quality ingredients and processes should be used to ensure superior levels of durability. A ripped glove eliminates the gloves' protection against fentanyl and puts the wearer at risk of accidental exposure. Learn about Eagle's proprietary glove quality testing program, Delta Zero, which third-party tests a range of Eagle gloves to ensure the highest levels of consistent performance and safety. Independently verifying them to be a glove durability your team can trust.
  4. Glove quality (AQL):
    The AQL, or acceptable quality level, of a disposable glove is a quality standard for measuring pinhole defects. Manufacturers test a random sample of gloves during the initial production and test for pinhole defects. The lower the AQL, the less defects the gloves have. An AQL of 1.5, for example, requires gloves be manufactured with no more than 15 failures for every 1,000 gloves produced. We recommend sourcing fentanyl gloves with an AQL of 1.5 or less.
  5. Glove color:
    It is a good practice to source fentanyl protective gloves in darker colors (i.e. black or blue) so white powder contamination can be more readily identified.

Proper fentanyl glove selection is imperative as the finely ground opioid powder can be absorbed transdermally via open cuts or wounds on hands and around fingernails. With the unique Eagle Standard ensuring consistent quality and performance, wearers can be confident of unbeatable protection. Eagle offers a range of fentanyl protective gloves, tested directly against a fentanyl solution, in differing thicknesses, colors and textures.

Proper Glove Use

In addition to equipping emergency, correctional and medical personnel with effective disposable gloves with fentanyl protection, the glove wearers must put on and take off the gloves properly in order to reduce the risk of cross-contamination and accidental exposure. Here is a video showing how to don and doff disposable gloves.

Eagle Protect Gloves with Fentanyl Protection

We offer a range of high-quality fentanyl gloves in a variety of colors, sizes, thicknesses and textures. Each glove offers superior fentanyl protection you can trust, but are best suited for different uses and tasks. If you have any questions or are unsure about which glove provides the protection you need, contact our team of experts to help.


Eagle Derma² nitrile exam gloves, our best selling fentanyl protective gloves, are exceptionally soft and lightweight (3mil), yet durable and strong, ideal for medical use and precision and tactile work.


Derma2 nitrile fentanyl gloves medical


    Eagle Sensitive nitrile exam gloves are 4mil thick, premium quality gloves for sensitive skin, providing superior barrier protection. An excellent choice for medical personnel who need a superior quality multi-purpose glove.

    • LOW DERMA™ enhanced for wears prone skin allergies and irritation
    • Protection against fentanyl, gastric acid, viruses and chemotherapy drugs
    • Delta Zero™ verified
    • Manufactured in a Gold level WRAP certified facility
    • Available in blue
    sensitive skin nitrile medical gloves with fentanyl protection


    Eagle Blue52 nitrile gloves work in almost every situation. At 5mil thick, they have been manufactured thicker for extra strength and durability. Ideal for first responders, police, security personnel and others who directly interact with the public.

    Blue52 fentanyl glove with protection


    Eagle Black Visible nitrile gloves have a 6mil thickness for improved strength and tear resistance. These fully textured black nitrile gloves provide the wearer with added grip and are ideal gloves for those who want to take extra precaution against ripping.

    • Fully textured for added grip
    • 6mil industrial-strength thickness
    • 9" cuff length for extra protection 
    • Resistance to bacteria, fungi and virus
    • Tested against fentanyl
    Black Visible nitrile gloves with fentanyl protection


    As America’s opioid crisis continues to increase, nitrile gloves with protection against fentanyl is becoming a part of standard equipment for emergency first responders, police departments, correctional facilities, medical staff and security personnel who have the highest risk of accidental exposure. Eagle Protect’s fentanyl gloves offer unbeatable performance and protection, eliminating risk for our customers.

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